Symbol
Name
ID

Nkx2-3
NK2 homeobox 3
MGI:97348

Phenotype annotations related to hematopoietic system

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

abnormal leukocyte migration

absent marginal zone B cells

decreased plasma cell number

decreased B cell number

decreased CD4-positive, alpha-beta T cell number

decreased T cell number

decreased lymphocyte cell number

increased leukocyte cell number

abnormal marginal zone B cell morphology

abnormal metallophilic macrophage morphology

abnormal spleen marginal zone macrophage morphology

abnormal spleen morphology

abnormal spleen red pulp morphology

intermingled spleen red and white pulp

decreased spleen weight

small spleen

spleen atrophy

abnormal spleen B cell follicle morphology

abnormal spleen primary B follicle morphology

abnormal spleen marginal sinus morphology

absent spleen marginal zone

abnormal spleen periarteriolar lymphoid sheath morphology

decreased spleen white pulp amount

abnormal splenic cell ratio

absent spleen

Availability

Mouse Genotype

Nkx2-3^tm1Hha/Nkx2-3^tm1Hha

Nkx2-3^tm1Rph/Nkx2-3^tm1Rph

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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